'Lab-on-a-glove' could bring nerve-agent detection to a wearer's fingertips: organophosphate nerve agents - can be used as deadly weapons. Now researchers have developed a fast way to detect the presence of such compounds in the field using a disposable "lab-on-a-glove." The report on the glove appears in the journal ACS Sensors.
Organophosphate nerve agents, including sarin and VX, are highly toxic and can prevent the nervous system from working properly. Organophosphate pesticides are far less potent but work in a similar way and can cause illness in people who are exposed to them, according to the U.S. Centers for Disease Control and Prevention.
Detecting either type of these sets of compounds accurately and quickly could help improve both defense and food security measures. So, Joseph Wang and colleagues set out to develop a wearable sensor that could meet the requirements of field detection.
The new wearable, flexible glove biosensor carries out the sampling and electrochemical biosensing steps on different fingers, with the thumb finger used for collecting the nerve-agent residues and an enzyme immobilized on the index finger. The researchers created stretchable inks to print the collection and sensing elements on these fingers.
